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Discussion on: Would you program a human?

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kspeakman profile image
Kasey Speakman

It's a tough call. I am a huge fan of the movie Gattaca precisely for the exploration of some of these questions. I could be on board with it for treating harsh diseases, but not for making designer children or "enhanced" humans. Such goals seem to align with very evil figures from history. And that's before we even get into the downsides. There's always a trade-off.

We've already seen it happen to food... not through direct editing but through generations of selective breeding. At this point, many of our commercially grown foods have a severe lack of genetic diversity. For example, wheat rust became a big problem in recent history. Growers were understandably focused on bigger yields. Selective breeding for that goal had inadvertently filtered out strains of wheat that had genetic resistance to the fungus.

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mortoray profile image
edA‑qa mort‑ora‑y

Yes, we don't need to edit genomes to create problems, it can however accelerate the timeline compared to selective breeding.

There are a lot of questions here, but it's inevitable that we will edit our genome. I also think that designer babies are inevitable -- prohibition rarely works. :/

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kspeakman profile image
Kasey Speakman • Edited

Oh, for sure gene editing is already happening in humans (see below). But I was speaking to your specific question of whether I would accept a position in "human programming". For disease treatment I probably would but beyond that, no way.

Check out this annual biotech guidebook, which highlights various advancements in biotech for the year. One of the articles (page 14) highlights human gene editing to combat Hunter syndrome. Much like the feeling I get after attending a computer security conference, upon reading this guide I feel both more knowledgeable and terrified at the future.

Edit: Also relevant, and I think generally a good foundation for ethics in biotech. UNESCO - Universal Declaration on the Human Genome and Human Rights

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mortoray profile image
edA‑qa mort‑ora‑y

Okay, so you'd accept a position in disease treatment... here comes that annoying part where I present uncomfortable options.

What if your company is treating diseases, but you're working on something more fundamental, a framework, or process, that will enable it. You know full well it'll also enable undesirable changes to the genome. Are you okay open-sourcing that foundation?

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kspeakman profile image
Kasey Speakman • Edited

But by the same token, what if I do something as benign as discover some breakthrough in app dev. So that solid apps can be made rapidly and cheaply. Maybe that also means resilient malware/ransomware can be made faster and more cheaply. Would it be unethical to do then?

Technology is neither good nor bad. It's a tool that is used for good or bad, depending on how the person wields it. So the answer is that I don't know. It would depend on the situation, including the people involved and the specific limitations of the tech.

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mortoray profile image
edA‑qa mort‑ora‑y

I'm going to have to side with technology is neither good nor bad. Thus it'd be ethical to develop tools that make malware easy, or make horrific genome edits easy.

I don't trust everybody, but the people I trust the least are those that do things in secret. Thus given the option between trying to keep a lid on technology, or making it open, I'm choosing open every time.