Yes. There is one tool I know of -- Responsive Image Breakpoints Generator. I love this tool for generating sets of one-offs in a pinch.
Unfortunately, I haven't got it to work like in the demo above. Here's an example.
Another thing I still have to do is go back and optimise the images from the generator. It spits out lots of images ;-)
Let me know if you get it to work or if you find something better!
P.s. The generator uses the cool HTML5 picture element. However, I generally work with background hero images.
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