I'm going to assume that your website doesn't exist just for the presentation of adverts.
I'm going to assume that you want people to visit and ha...
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There's one thing to keep in mind:
The big thing with the ads is that nobody (not the dev who puts the code in, nor the ad providers) checks if the ads are safe/legit. When I mean safe/legit, I mean "does not execute a ton of Javascript that makes browsers slow to a crawl or infect them with malware."
If you have set your ads to restrict to only images(no audio, no video, no Javascript, no Flash), and declare that with an "ad policy", you're more likely to have folks turn off the ad blocker. But if you insist on all the ads, you'll find more people blocking them, and you're fighting a losing battle.
... and don't forget that entire domains could be blocked by one of the many hosts files out there that maintain a list of "pure" advertising hostnames.