Simply use reduce and Map:
[{a: 1, b: 2, c: 3}, {a: 2, b: 3, c: 4}, {a: 1, b: 2, c: 5}].reduce((p, c) => p.set([c.a, c.b].join('|'), c), new Map()).values()
Edit: For selecting the first value, use Map.has before setting the value.
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Simply use reduce and Map:
[{a: 1, b: 2, c: 3}, {a: 2, b: 3, c: 4}, {a: 1, b: 2, c: 5}].reduce((p, c) => p.set([c.a, c.b].join('|'), c), new Map()).values()
Edit: For selecting the first value, use Map.has before setting the value.