1.) This may require some research depending on OS. When someone steps away, make sure the shortcut is enabled for it. But enabling high contrast mode.
2.) Take a screenshot of their desktop, remove everything on their desktop. Set their wallpaper to the screenshot you took. They will be so confused as to why they can not click anything on their desktop.
For further actions, you may consider blocking this person and/or reporting abuse
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A few simple ones:
1.) This may require some research depending on OS. When someone steps away, make sure the shortcut is enabled for it. But enabling high contrast mode.
2.) Take a screenshot of their desktop, remove everything on their desktop. Set their wallpaper to the screenshot you took. They will be so confused as to why they can not click anything on their desktop.