I've been a professional C, Perl, PHP and Python developer.
I'm an ex-sysadmin from the late 20th century.
These days I do more Javascript and CSS and whatnot, and promote UX and accessibility.
I would say to use Sass until nesting becomes part of CSS, and to write semantic markup. You don't need anything else, and things like Bootstrap hold back long-term progress in favour of short-term ease.
I've known a couple of people who lean on Bootstrap and use it to avoid learning the fundamentals. I know there are a million things to learn, and it's easy to feel like you're missing out on the latest shiny tool, but I genuinely believe it's unprofessional to not gain at least base proficiency with the fundamentals.
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I would say to use Sass until nesting becomes part of CSS, and to write semantic markup. You don't need anything else, and things like Bootstrap hold back long-term progress in favour of short-term ease.
+1 on this.
I've known a couple of people who lean on Bootstrap and use it to avoid learning the fundamentals. I know there are a million things to learn, and it's easy to feel like you're missing out on the latest shiny tool, but I genuinely believe it's unprofessional to not gain at least base proficiency with the fundamentals.