"Plain" Django can be used with templates to have a webapp without any front end framework.
However, you can use Django Rest Framework (DRF for short), to encapsulate all the backend task within Django, and use a Front end framework like React or Angular for styling and front end logic.
Vue, as a progressive front end framework, you could use it even without DRF, just adding it to your templates. But of course, a more clean approach is the one that you want.
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"Plain" Django can be used with templates to have a webapp without any front end framework.
However, you can use Django Rest Framework (DRF for short), to encapsulate all the backend task within Django, and use a Front end framework like React or Angular for styling and front end logic.
Vue, as a progressive front end framework, you could use it even without DRF, just adding it to your templates. But of course, a more clean approach is the one that you want.