I recently started using fomantic-ui.com/ and use jQuery with that all the time now. I didn't for quite a while and rolled completely custom, since I don't use React, Angular, Vue, etc. But switching to Fomantic feels like a nice breath of fresh air at the moment.
That is until the next CSS library uses Custom Elements and it'll be great. I'm still salty they got rid of link[rel=import]
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