I suppose it doesn't matter what you use to make something, as long as your having a good time. Tailwind looks pretty cool, haven't actually used it for anything yet though.
Tailwind does make putting a UI together simpler.
If you do use it, definitely use it with Purgecss though. It gives you a ton of utility classes by default—color utilities for text, backgrounds, and borders; responsive variant utilities for pretty much everything... Using Purgecss when building your production CSS shrinks it to an unbelievably small size.
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