I have started using uWSGI and NGINX with sockets. It has been better so far and was also easy to deploy. I have done https with Let's Encrypt on NGINX for the API.
followed below for uWSGI and NGINX:
How To Serve Django Applications with uWSGI and Nginx on CentOS 7
followed below for ssl on NGINX:
How To Secure Nginx with Let's Encrypt on CentOS 7
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