Living in the Bay Area, I'm a little shocked by the number of people here with a separate room that they can use as a home office.
As someone living in a shared one-bedroom apartment, I would say that I've benefitted from a good pair of noise-canceling headphones, but one thing that I haven't seen mentioned here is good cable-management. I recently bought a desk with integrated cable-management and power-strip and it's made my confined workspace feel a lot more manageable.
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