IIRC, USB allows for up to 127 devices, including hubs in that total, per host controller. Not sure if this is still the case for USB-C?
While getting a degree 20-odd years ago, I worked retail, and for some reason that 127 number always stuck... ;)
Also, some internal stuff is already using the USB bus, like the camera. You can check those in 'Apple menu'--> about this Mac --> system report
EDIT: the Apple T1 chip is also on the USB bus on my 2016 MacBook Pro, from system report. Now I know ;)
From reddit.com/r/macbook/comments/ge22...
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