Molence Bio released Mol-1, its first biomolecular foundation model, with source code and base weights open-sourced. On FoldBench-AB it reaches 75.0% success (vs Isomorphic IsoDDE 75.6%) and reportedly beats Anthropic's published large-complex results; antibody de novo designs were lab-verified.
Key points
- FoldBench-AB: 75.0% (vs Isomorphic IsoDDE 75.6%)
- Single model covers antibody, protein, peptide, small-molecule, molecular glue
- Source code plus base weights open-sourced; antibody designs lab-verified
- Released November 4, 2026
Full write-up: https://www.threerouter.com/blog/305
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