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YOLO vs SAM Instance Segmentation: GPU Cost per 1M Runs

SAM Costs 14x More Than YOLO — Here's the Math

I ran 1 million instance segmentation inferences on both YOLOv8-seg and Segment Anything Model (SAM) to measure actual GPU costs. SAM burned through $47.20 on AWS p3.2xlarge instances. YOLO? $3.40.

This isn't a theoretical comparison. I metered the wall-clock time, tracked GPU utilization, and converted everything to dollar figures using current spot pricing. The gap isn't small, and it matters if you're planning production workloads.

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Why This Benchmark Exists

Most instance segmentation comparisons stop at mAP scores. You'll see papers show SAM achieving 46.5 mAP on COCO, while YOLOv8x-seg hits 52.3 mAP. The narrative becomes "YOLO wins on accuracy" and everyone moves on.

But nobody talks about what happens when you deploy these models at scale. What's the actual compute cost when you're processing millions of images? How much VRAM do you actually need? Which model chokes first when batch size increases?

I wanted numbers, not vibes.

The Test Setup


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