DEV Community

vidgastech
vidgastech

Posted on

4-Bromopyrazole (CAS 2075-45-8) in Ruxolitinib Intermediates: A Crucial Step in Targeted Cancer Therapy

Published by Vidgastech – Your Partner in API & Intermediate Supply

🔍 Introduction

In the ever-evolving landscape of pharmaceutical manufacturing, the role of specialty intermediates has become more vital than ever. One such key compound is 4-Bromopyrazole (CAS No. 2075-45-8) — a critical building block used in the synthesis of Ruxolitinib, a highly targeted JAK1/JAK2 inhibitor used in cancer and immune disorder therapies.

At Vidgastech, we specialize in supplying high-purity chemical intermediates like 4-Bromopyrazole to meet the exacting standards of the global pharmaceutical industry.

💡 What is 4-Bromopyrazole?

4-Bromopyrazole is a halogenated heterocyclic compound with the molecular formula C3H3BrN2. It is widely utilized in organic synthesis, particularly in the creation of pharmaceutical agents due to its reactivity and versatility.

CAS Number: 2075-45-8

Molecular Weight: 146.97 g/mol

Appearance: White to off-white crystalline powder

Purity: ≥ 99% (Available on request)

💊 Role in Ruxolitinib Synthesis

Ruxolitinib is an FDA-approved drug used to treat myelofibrosis, polycythemia vera, and certain rare blood disorders. The synthesis of Ruxolitinib involves multiple complex steps where 4-Bromopyrazole acts as a key intermediate for constructing the drug’s core structure.

Its presence ensures:

High yield and purity of the final API

Structural stability during chemical transformations

Compatibility with other synthesis reagents

🏭 Why Choose Vidgastech for 4-Bromopyrazole?

Vidgastech is a trusted name in the chemical and pharmaceutical industries, known for delivering quality-driven and cost-effective API intermediates across the globe. When you source 4-Bromopyrazole from Vidgastech, you benefit from:

✅ High Purity Grades (available with COA)
✅ Flexible Packaging for lab to commercial scale
✅ Custom Synthesis and Contract Manufacturing Services
✅ Regulatory Support Documents (if required)
✅ Global Shipping & Timely Delivery

🌐 Applications Beyond Ruxolitinib

While primarily used in Ruxolitinib production, 4-Bromopyrazole also finds applications in:

Synthesis of heterocyclic compounds

Development of kinase inhibitors

Medicinal chemistry research

Custom drug molecule development

📦 Bulk & Custom Orders Available

Whether you're an R&D lab or a commercial pharmaceutical manufacturer, Vidgastech can supply 4-Bromopyrazole tailored to your needs — from gram-scale to bulk quantities.

📞 Get in Touch

Interested in sourcing 4-Bromopyrazole or other Ruxolitinib intermediates?
Connect with Vidgastech today for pricing, samples, and tech support.

🌐 Website: www.vidgastech.com

Top comments (0)