I tried but could not get used to having one monitor vertically and one horizontally.
I used vertical setup more for reading documentation more than coding itself.
I have a similar setup as Wesley. Two 22 inch monitors, one each side of my mac book.
Browser and evernote goes to the external monitor-1 (To the Left). I don't keep any other windows besides the work(mostly Android studio) that I'm currently working on my MacBook screen.
External Monitor 2 is set vertically which I use it for terminal primarily for the purpose of logs. I do open the terminal in my MacBook Screen, If I'm writing any script. But usually my terminals are in the vertical monitor.
Initially it was little weird to look at vertical monitor. But I got used to it. Been using it for 4 months now.
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