Am I a germophobe? No. I just hate the look of the keyboard on my screen every other day. It really bothers me when I see things on my screen that doesn't belong there. So I wipe both the screen, with microfiber and the keyboard with a regular cloth. Then, just to be extra careful I have the original thingie that came with the computer to separate the keyboard and screen. Now if that doesn't scream geek I don't know what does. After reading other people's answers to this qustion I feel a little creepy. So to answer the question after all that I would say at least once a day.
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