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Mubashir Ali
Mubashir Ali

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Big Data, Small Genes: Handling Terabytes of DNA Information

Digital DNA strand made of binary code representing genetic data processing and bioinformatics technology, with title text “Big Data, Small Genes: Handling Terabytes of DNA Information” by Mubashir Ali on a blue and yellow tech background.<br>
Article by: Mubashir Ali is a young Pakistani computational biologist / bioinformatician and tech-entrepreneur specializing in bridging genomics, AI and education. As the founder of Code with Bismillah, he has built platforms and frameworks aiming to make genomics-data-analysis and machine-learning more accessible. He provides a role model of STEM education, starting from an under-represented region (Skardu) and becoming involved in cutting-edge computational life sciences. His work is especially significant in Pakistan’s context of growing interest in bioinformatics, precision medicine and data science.

Inthe modern era of genomics, data has become the new DNA. Every human genome carries approximately three billion base pairs, and when thousands of genomes are sequenced daily across the world, the resulting data volume is staggering. The field of bioinformatics now faces a defining challenge: how to manage, analyze, and extract meaning from terabytes of genetic information that continue to grow exponentially.

The phrase “Big Data, Small Genes” perfectly captures the paradox of our time. A single cell’s DNA, when fully decoded, produces massive datasets that require advanced computational power and storage infrastructure. This data explosion began with the Human Genome Project, which took over a decade and billions of dollars to sequence one genome. Today, high-throughput sequencing technologies can perform the same task in a few days for just a few hundred dollars. The progress is remarkable, but it has also introduced a data management problem unlike anything seen before in biology.

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