I've built dashboards with bootstrap framework. Overall - it's just a framework. It'll help you lay out your components, and using the utility classes are helpful for a lot of the visual elements in common Project Management software.
If the bottleneck was CSS file size (which it rarely is on the projects I've built), It would be difficult to refactor the project out of bootstrap because of how dependent a lot of the code is on bootstrap. But that's not a con -- it was a fast deployment VS many many more work hours to find all the right visual libraries to display data.
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