Clinical ML evaluation typically emphasizes:
• Discrimination
• Calibration
• Cross-validation performance
These are foundational.
But insufficient.
When deployed, a model:
• Changes clinician workflow
• Alters escalation patterns
• Consumes limited resources
• Introduces false positive burden
This makes it an intervention.
Intervention-level evaluation requires:
Prospective impact studies
Cost-effectiveness modeling
Equity audits
Workflow load assessment
Continuous monitoring pipelines
For example, a sepsis prediction model may:
• Improve early antibiotic delivery
• Increase unnecessary ICU admissions
• Trigger over-testing
Only system-level measurement reveals net benefit.
Healthcare ML must evolve toward intervention science.
My background:
Pharmacist (12 years)
MPH
MSc Data Science – Precision Medicine
Focused on decision-aware and impact-measured clinical AI systems.
You can explore my broader work here:
Medium: https://medium.com/@fora12.12am
Substack: https://substack.com/@glazizzo
Feedcoyote: https://feedcoyote.com/onyedikachi-ikenna-onwurah
Facebook: https://www.facebook.com/61587376550475/
LinkedIn: www.linkedin.com/in/onyedikachi-ikenna-onwurah-0a8523162
Open to remote roles and collaborations in healthcare AI and digital health systems.
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