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I Built an API That Replaces Hours of FDA Drug Safety Analysis With One Call

#ai #python #database #opensource

Last month I needed to answer a simple question: Is Ozempic safer than Mounjaro?

To answer that using public FDA data, I had to:

  • Query openFDA adverse events (54,647 raw records for Ozempic alone)
  • Query openFDA recalls (separate endpoint, different search syntax)
  • Query openFDA labels (third endpoint, another schema)
  • Repeat all three for Mounjaro
  • Cross-reference with SEC filings (fourth API)

That is 6+ API calls across 4 different systems. Hours of work for one question.

So we built an API that does it in one call.

One Call, One Answer 

GET /intelligence/v2/compare?drugs=ozempic,mounjaro,trulicity
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Response:

OZEMPIC (Novo Nordisk / NVO)
  Serious rate: 44.9%  |  Death rate: 1.58%  |  Recalls: 2

MOUNJARO (Eli Lilly / LLY)
  Serious rate: 7.3%   |  Death rate: 0.14%  |  Recalls: 0

Winner (lowest serious rate): MOUNJARO
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Five seconds. Three drugs compared. Company linkage included automatically.

What Else It Does

This is not just a wrapper around openFDA. The engine combines data from 4 government sources and adds intelligence that does not exist anywhere else as an API:

Pharmacovigilance Signal Detection

Uses PRR and ROR to detect adverse reactions at disproportionate rates. For Keytruda, it found 44 safety signals including Tumour pseudoprogression (PRR=32.08).

Company Portfolio Risk

Query by stock ticker, get the full drug portfolio with individual risk scores.

AI Analyst Briefs

Claude-powered safety assessments combining all data sources into natural language.

Natural Language Query

Ask in plain English and get a structured, sourced answer.

The Numbers

  • 358 drugs tracked
  • 1,000,000+ adverse event reports from FDA FAERS
  • 691 recalls, 2,221 label changes
  • 156 biotech companies linked to SEC filings
  • 25 API endpoints
  • 19 MCP tools for AI agent integration

Try It

Free tier: 100 calls/day, no credit card.

MCP for AI Agents

Listed on the official MCP registry. 19 tools available.

{
  "mcpServers": {
    "pharma-signal": {
      "url": "https://api.pharma-signal.com/mcp/"
    }
  }
}
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Feedback welcome. Real FDA data updated daily.

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