If you want to avoid JS fatigue, remember that you don't have to learn everything. I think it's enough just to be aware of the new tools, what their use cases are, and their pros/cons.
With that information, the next time you create a new project and you have to decide which stack to use, you'll have those libraries as available options.
You can also focus on those tools that appear in job postings, especially if your main focus is to get a job. For example, there are lots of job postings that require React. If you want to become more employable, learning that framework is a good idea.
Every now and then, it's not a bad idea to pick up a library that you find particularly interesting, even if it's just to create a toy project. That's what I recently did with Svelte, for example.